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Updated: Wed, 10/02/2024 - 13:45

From Saturday, Oct. 5 through Monday, Oct. 7, the Downtown and Macdonald Campuses will be open only to ƻԺ students, employees and essential visitors. Many classes will be held online. Remote work required where possible. See Campus Public Safety website for details.


Du samedi 5 octobre au lundi 7 octobre, le campus du centre-ville et le campus Macdonald ne seront accessibles qu’aux étudiants et aux membres du personnel de l’Université ƻԺ, ainsi qu’aux visiteurs essentiels. De nombreux cours auront lieu en ligne. Le personnel devra travailler à distance, si possible. Voir le site Web de la Direction de la protection et de la prévention pour plus de détails.

Standard Operating Procedures (SOPs)

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On this page:📄 Animal Incident Report Form 📄 Analgesia 📄 Anesthesia 📄 ​​​​​​​Animal Care 📄 ​​​​​​​Crisis Management and Communication Plan SOP 📄 ​​​​​​​Experimental Guidelines 📄 ​​​​​​​Euthanasia 📄 ​​​​​​​MacDonald Campus - Dairy Facility SOPs 📄 ​​​​​​​MacDonald Campus - Poultry Facility SOPs 📄 ​​​​​​​MacDonald Campus - Swine Facility SOPs 📄 ​​​​​​​Occupational Health and Safety 📄 ​​​​​​​PHAC Biohazard Information 📄 Record Keeping, Storage and Disposal of Controlled Substances 📄 ​​​​​​​Surgery 📄 ​​​​​​​Veterinary Care

Standard Operating Procedures (SOPs) provide a detailed description of commonly used procedures. SOPs offer investigators an alternative to writing detailed procedures in their protocol.

Note that the use of the words ‘should’ and ‘must’ in these SOPs is consistent with their defined use in Canadian Council on Animal Care (CCAC) guidelines. The term 'should' indicates an obligation, for which any exceptions must be justified to, and approved by, an Animal Care Committee. The term 'must' indicates a mandatory requirement.

Any deviation from the approved procedures must be clearly described and justified in the Animal Use Protocol application in AMS. Approval of the protocol indicates approval of the deviation from the SOP for that project only.

The following Standard Operating Procedures (SOPs) were created and/or revised by the Veterinary Committee and approved by the Animal Policy and Welfare Oversight Committee (APWOC), 3 ƻԺ FACCs or a specific FACC where applicable. They are reviewed every 3 years at most.

The SOPs here are mainly for ƻԺ sites. If you are in an affiliated Research Institute, please contact your FACC Coordinator to find out if these (or which) apply to your site and where to find your local SOPs.

The Coordinator at:

  • The RI-MUHC (MGH and Glen site) as well as the Shriners Hospitals for Children can be reached via this facc.admin [at] muhc.mcgill.ca (email).
  • The Douglas Mental Health University Institute can be reached via this tara.thomson.comtl [at] ssss.gouv.qc.ca (email).
  • The Lady Davis Institute of the JGH can be reached via this darleen.element [at] ladydavis.ca (email).

If you have questions or have a recommendation to make, please send an animalcare [at] mcgill.ca (email) or talk to the Veterinarian in your area.

Approved SOPs Below

Analgesia

PDF iconSOP 101-Rodent AnalgesiaREVISED PDF iconSOP 107-Bird Analgesia
PDF iconSOP 102-Rabbit Analgesia PDF iconSOP 108-Fish Aquatic Amphibian Reptile Analgesia
PDF iconSOP 103-NHP Analgesia PDF iconSOP 109-Ruminant Analgesia
PDF iconSOP 105-Cat Analgesia PDF iconSOP 122-Ferret Analgesia
PDF iconSOP 106-Swine Analgesia

Anesthesia

PDF iconSOP 110 - Mouse AnesthesiaREVISED PDF iconSOP 118 - Fish and Aquatic Amphibian Anesthesia
PDF iconSOP 111 - Rat AnesthesiaREVISED PDF iconSOP 119 - Swine Anesthesia
PDF iconSOP 115 - NHP AnesthesiaREVISED PDF iconSOP 120 - Rodent Anesthesia Protocol Lung Physiology MeasurementsREVISED
PDF iconSOP 117 - Cat Anesthesia PDF iconSOP 121 - Bird AnesthesiaREVISED

Surgery

PDF iconSOP 201 - Rodent Surgery PDF icon SOP 205 - Rodent Tumor Resection
PDF iconSOP 202 - Rodent Stereotaxic Surgery PDF icon SOP 206 - Rodent Ovariectomy
PDF iconSOP 203 - Large Animal Surgery PDF icon SOP 207 - Rodent Castration
PDF iconSOP 204 - Xenopus Egg and Oocyte Collection PDF icon SOP 208 - Rodent Mammary Fat Pad Injection

Euthanasia

PDF iconSOP 301 - Rodent EuthanasiaREVISED PDF iconSOP 304 - Avian Euthanasia
PDF iconSOP 302 - Large Animal EuthanasiaREVISED PDF iconSOP 305 - Transcardiac Perfusion
PDF iconSOP 303 - Fish and Aquatic Amphibian EuthanasiaREVISED

Experimental Guidelines

PDF iconƻԺ's EHS SOP 401 - Controlled Substances PDF iconSOP 410 - Humane Intervention Points
PDF iconSOP 402 - Tissue Collection for Genotyping - Mice PDF iconSOP 412 - Humane Intervention Points for Aging Rodents
PDF iconSOP 403 - Guidelines Blood Collection Volumes and Frequency PDF iconSOP 413 - Tissue Collection for Genotyping - Rats
PDF iconSOP 404 - Substance Administration PDF iconSOP 415 - Humane Intervention Points for Rodent Cancer Models
PDF iconSOP 405 - Monoclonal Antibody Production - Mice PDF icon SOP 417 - Food and Water Restriction in Rodents
PDF iconSOP 406 - Polyclonal Antibody Production - Rabbits PDF icon SOP 418 - Humane Intervention Points for Animals Used in Training
PDF iconSOP 407 - Polyclonal Antibody Production - Rats PDF icon SOP 419 - Humane Intervention Points for Rodents Models Involving Paralysis
PDF icon SOP 409 - Maintaining Clinical Records PDF icon SOP 420 - Estrous Cycle Assessment in Rodents
This Monitoring Log is to be prepared by the Facility Animal Care Committee as per the approved Animal Use Protocol:
FileMonitoring log TEMPLATE
FileCMARC NHP Activity Tracking and Procedures Requiring Anesthesia Log

Animal Care

PDF iconSOP 501- Animal Transport and Use Outside of Animal Facilities PDF iconSOP 522 - Environmental Enrichment Program for FishNEW
PDF iconSOP 502 - Environmental Enrichment Program for RodentsREVISED PDF iconSOP 523 -Environmental Enrichment Program for AmphibiansNEW
PDF iconSOP 504 - Environmental Enrichment Program for Rabbits PDF iconSOP 525 - Cat Husbandry
PDF iconSOP 505 - Environmental Enrichment Program for Hamsters PDF iconSOP 526 - Environmental Enrichment Program for CatsNEW
PDF iconSOP 506 - Environmental Enrichment Program for Guinea Pigs
PDF iconSOP 527 - Finch Husbandry
PDF iconSOP 507 - Environmental Enrichment Program for NHPsREVISED PDF iconSOP 528 - Environmental Enrichment Program for BirdsNEW
PDF iconSOP 508 - Rodent HusbandryREVISED PDF iconSOP 531 - Animal Acquisition Receiving and Acclimation
PDF iconSOP 513 - Marmoset Husbandry PDF iconSOP 532 - Vermin Control ProgramREVISED
PDF iconSOP 515 - Marmoset Feeding PDF iconSOP 533 - Microbiological Monitoring Program
PDF iconSOP 516- Marmoset Cage Changing
PDF iconSOP 536 - Procedure Room Maintenance
PDF iconSOP 517 - Marmoset Room Sanitation PDF iconSOP 537 - Working in Laminar Flow Hood or Animal Transfer Station or Biological Safety Cabinet
PDF iconSOP 518 - Transportation of NHPs Between Facilities PDF iconSOP 540 - Operating Room Maintenance
PDF iconSOP 519 - Aquatic Animal Husbandry PDF iconSOP 541 - Vendor Approval for Animal Feed and Bedding Suppliers
PDF iconSOP 521 - Macaque Husbandry

Veterinary Care

PDF iconSOP 601 - Veterinary Care Program PDF iconSOP 614 - Guidelines on Wire-Bottom Caging for Rodents
PDF iconSOP 602 - Rodent Health Monitoring Program PDF iconSOP 615 - Rodent Irradiation
PDF iconSOP 603 - Rodent Quarantine Program PDF iconSOP 616 - Rodent Identification
PDF iconSOP 604 - Bioexclusion Levels for Rodents PDF iconSOP 619 - Common Rodent Treatment
PDF iconSOP 605 - Rodent Import
PDF iconSOP 622 - Marmoset Health Monitoring Program
PDF iconSOP 606 - Reporting Concerns Regarding Animal Care and Use PDF iconSOP 623 - Marmoset Breeding Colony Management
PDF iconSOP 607 - Long-term Housing PDF iconSOP 626 - Macaque Health Monitoring Program
PDF iconSOP 608 - Mouse Breeding Colony Management PDF iconSOP 631 - Macaque Herpes B Testing
PDF iconSOP 609 - Rat Breeding Colony Management PDF iconSOP 632 - Animal Welfare Assessment
PDF iconSOP 610 - Testing of Biological Material
PDF iconSOP 636 - Storage and Transport of Primate Tissues
PDF iconSOP 611 - Excluded Pathogens - Rodent Facilities PDF iconSOP 637 - Cumulative Endpoints
PDF iconSOP 612 - Working with Immunodeficient Mice PDF iconSOP 638 - Positive Reinforcement Training
PDF iconSOP 613 - Working with Rodents in the Imaging Facility

Occupational Health and Safety

PDF iconSOP 701 - Macaque-Related Injury PDF iconSOP 709 - Waste Anesthetic Gas ScavengingREVISED
PDF iconSOP 702 - Animal Related Injury PDF iconSOP 710 - Personal Protective Equipment Requirements
PDF iconSOP 703 - Use of Viral Vectors in Neuroscience - Rodents PDF iconSOP 715 - Use of Cisplatin in Rodents
PDF iconSOP 705 - Animal Containment Level 2 – Rodents PDF iconSOP 716 - Use of Doxorubicin in Rodents
PDF iconSOP 706 - Use of Hazardous Agents in Rodents - General PDF iconSOP 717- Use of Tamoxifen in Rodents
PDF iconSOP 708 - Use of Streptozotocin in Rodents

MacDonald Campus - Dairy Facility SOPs

PDF iconDC-101Bio Security Cattle Complex PDF iconDC-602 Milk House Post-Milk Wash
PDF iconDC-121 Flushing Gutters in the Dairy Barn PDF iconDC-603 Bulk Tank Sanitizing Procedure
PDF iconDC-131 Environmental Monitoring and Maintenance PDF iconDC-604 Box Stall Milker Sanitization
PDF iconDC-206 Box Stall Sanitation PDF iconDC-605 Preparing Cows for Milking
PDF iconDC-207 Tie Stall Sanitation
PDF iconDC-606 Post-Milking Procedure
PDF iconDC-208 Heifer Pen_Stall Sanitation PDF iconDC-607 Milking Procedure
PDF iconDC-209 Calf Pen Sanitation PDF iconDC-608 Milking Fresh Cows
PDF iconDC-210 Acquisition of Dairy Cattle PDF iconDC-609 Milking Pail Cows
PDF iconDC-211 Loading and Transporting Cattle PDF iconDC-610 Milking Cows with Box Stall Milker
PDF iconDC-212 Handling and Moving Cattle
PDF iconDC-611 Milking Staphylococcus Aureus Positive Cows
PDF iconDC-215 Selecting Appropriate Stalls for Tethered Cattle PDF iconDC-612 Milking Antibiotic Treated Cows
PDF iconDC-230 Environmental Enrichment Program for Dairy Cattle PDF iconDC-613 Accidental Milking Antibiotic Treated Cows into Milking System
PDF iconDC-301 Body Condition Scoring for Dairy Cows PDF iconDC-614 Dry Treating Cows
PDF iconDC-302 Lameness Scoring for Dairy Cows PDF iconDC-615 Milk Sampling
PDF iconDC-303 Injury Scoring for Dairy Cows
PDF iconDC-616 Milk Culturing
PDF iconDC-304 Cleanliness Assessment for Dairy Cows PDF iconDC-617 California Mastitis Test (CMT)
PDF iconDC-305 Mastitis Monitoring and Detection PDF iconDC-701 Substance Administration for Dairy Cattle
PDF iconDC-306 Mastitis Treatment PDF iconDC-702 Blood Sample Collection
PDF iconDC-307 Extra Teat Removal Calves PDF iconDC-712 Pre- and Post-Operative Procedures and Long-Term Care of Fistulated Cows
PDF iconDC-311 Managing Downed Cattle
PDF iconDC-713 Rumen Content Collection from Fistulated Cow
PDF iconDC-315 Cumulative Endpoints Dairy Cattle PDF iconDC-714 Transfaunation
PDF iconDC-360 Outdoor Exercise Habituation of Tie-Stall Cattle PDF iconDC-715 Controlled Internal Drug Release Silicone Device Insertion
PDF iconDC-361 Outdoor Exercise of Tie-Stall Dairy Cattle PDF iconDC-A-1A Environmental Monitoring Log
PDF iconDC-400 Heat Detection and Breeding PDF iconDC-A-2A Cattle Transport Decision Tree
PDF iconDC-405 Pre-Partum Preparation of Dairy Cattle
PDF iconDC-A-4A Heat Cycle, Signs and Conception rates of Dairy Cattle
PDF iconDC-406 Post-Partum Care of Dairy Cattle PDF iconDC-A-4B Signs of Heat in Dairy Cattle
PDF iconDC-407 Calving Cows-Heifers PDF iconDC-A-4C Factors Influencing Heat Detection in Dairy Cattle
PDF iconDC-501 Colostrum Management PDF iconDC-A-4D Leg Band Color Legend
PDF iconDC-502 Milk Replacer Preparation PDF iconDC-A-5A Colostrum Quality Readings
PDF iconDC-503 Calf Identification
PDF iconDC-A-5B Newborn Heifer Feeding Log
PDF iconDC-504 Newborn Calf Care PDF iconDC-A-6A Herd Health Scoring Record
PDF iconDC-505 Calf Care Feeding PDF iconDC-A-6B Injury Scoring Record for Dairy Cows
PDF iconDC-506 Tube Feeding a Calf PDF iconDC-A-6C Lameness Scoring Record for Dairy Cows
PDF iconDC-601 Milk House Pre-Milking Set Up PDF iconDC-A-6D Cleanliness Assessment Record for Dairy Cows

MacDonald Campus - Poultry Facility SOPs

PDF iconPU-101 Biosecurity Poultry Unit PDF iconPU-2010 Environmental Enrichment Program for Poultry
PDF iconPU-202 Environmental Management Broiler PDF iconPU-520 Poultry Euthanasia
PDF iconPU-203 Broiler Barn Preparation PDF iconPU-A-0 Donald McQueen Shaver Poultry Unit Floor Plan
PDF iconPU-204 Sanitation Procedure Broiler Barn PDF iconPU-A-2A Broiler Temperature Management Chart
PDF iconPU-205 Manure Management Broiler PDF iconPU-A-3A Should this bird be loaded - Decision tree
PDF iconPU-208 Loading and Transporting Broilers PDF iconPU-A-3B Handling Guidelines for Catching Crews
PDF iconPU-209 Receiving Broiler Chicks and Poults

MacDonald Campus - Swine Facility SOPs

PDF iconSW-2010 Environmental Enrichment Program for Swine

Requirements on Record Keeping, Storage and Disposal of Controlled Substances

Refer to the ƻԺ Environmental Health and Safety Office'sSOP 401 on Cannabis and Controlled Substances.

Research Institutes of affiliated hospitalsshould contact their local Safety Office or EHS Officer.

For ƻԺ researchers and instructors:

  • All Principal Investigators (PIs) intending to use controlled substances (and cannabis) need to contact thedomenic.dulisse [at] mcgill.ca (EHS Cannabis & Controlled Substances Officer)for notification and exemption processing. The PI's information is added to EHS' records and follow ups are performed. All research and teaching involving animals MUST have an approved Animal Use Protocol before being considered for an exemption.
  • The EHS' MyLab software migration will allow for this information to be kept and tracked within MyLab. Permits will be issued to PIs using cannabis and controlled substances.
  • Training for cannabis and controlled substance will be mandatory for all users. They will be granted a permit contingent on successful completion of the training which is every 2 years.
  • An inspection checklist has been created specifically for cannabis and controlled substances in labs. PIs must follow Health Canada’s directive on physical security, while ƻԺ veterinarians do not (they are responsible for the safe keeping of their drugs and reporting to Health Canada).
  • A Cannabis compliance committee is being set up with the Director of EHS and will allow for better decision making and department awareness. This will be done for controlled substances in the near future.
  • Controlled drug suppliers have been added to the ƻԺ Market Place (MMP) and follow the same rules as radiation materials. Note that all orders must be approved by the cannabis and controlled substance officer.
  • A revisedSOP #401 for controlled substances is now posted on the EHS site. There is more information onEHS' website for the Cannabis and Controlled Substance Compliance Program (CCSCP), Environmental Health and Safety, ƻԺ.

PHAC Biohazard Information

The Public Health Agency of Canada has implemented since December 2015, new regulations pertaining to the use of Human Pathogens and Toxins. Background information can be found onand details on the regulation.

In order to work with Biohazardous Materials in a laboratory setting, researchers must complete an “Application to Use Biohazardous Materials”. These applications are reviewed and approved by ƻԺ's Environmental Health and Safety Office (not the Animal Care Committee). Approval of the Application means that the researcher is compliant with the Biosafety Program which includes lab inspections and training.

Useful links(these two are also available as free Apps for a smartphone or tablet as well):

  • (CBS), 2nd edition.
  • Public Health Agency of Canada(PSDS).

ƻԺ Animal Incident Report Form:

FileƻԺ Animal Care Incident Report Form

Template for a Crisis Management and Communication Plan SOP:

FileSOP TEMPLATE for Crisis Management Plan

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